Author Question: What would be primary therapeutic outcome(s) expected from fludrocortisone (Florinef) therapy? ... (Read 52 times)

Zoey63294 · **on:** Jul 24, 2018

What would be primary therapeutic outcome(s) expected from fludrocortisone (Florinef) therapy? (Select all that apply.)

a. Reduced inflammation
b. Pain relief
c. Blood pressure control
d. Restored fluid and electrolyte balance

Question 2

What are functions of glucocorticoids? (Select all that apply.)

a. Maintain fluid and electrolyte balance
b. Have anti-inflammatory activities
c. Regulate protein, carbohydrate, and fat metabolism
d. Provide relief of rheumatoid arthritis
e. Include aldosterone

yasmina · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: C, D
Fludrocortisone is used in combination with glucocorticoids to treat salt-losing adrenogenital syndrome for blood pressure control and to restore fluid and electrolyte balance. Because fludrocortisone has mineralocorticoid and glucocorticoid effects, it has an anti-inflammatory action. However, this is not one of the primary therapeutic outcomes expected from fludrocortisone therapy. Fludrocortisone does not relieve pain.

Answer to Question 2

ANS: B, C, D
Glucocorticoids have anti-inflammatory and antiallergenic activities. Glucocorticoids (cortisone, hydrocortisone, prednisone, and others) regulate carbohydrate, protein, and fat metabolism. Glucocorticoids are effective for immunosuppression in the treatment of certain cancers, organ transplantation, autoimmune diseases (e.g., lupus erythematosus, dermatomyositis, rheumatoid arthritis), relief of allergic manifestations (e.g., serum sickness, severe hay fever, status asthmaticus), and treatment of shock. In addition, they may be used to treat nausea and vomiting resulting from chemotherapy. Glucocorticoids do not maintain fluid and electrolyte imbalance. Glucocorticoids do not include aldosterone.