Author Question: Which drug is used to obtain vasodilation in the treatment of chronic heart failure? a. ACTH b. ... (Read 15 times)

folubunmi · **on:** Jul 24, 2018

Which drug is used to obtain vasodilation in the treatment of chronic heart failure?

a. ACTH
b. ACE inhibitors
c. ARBs
d. ANB agents

Question 2

Which action of ACE inhibitors results in effective treatment of heart failure?

a. Increased afterload
b. Increased aldosterone
c. Increased preload
d. Increased cardiac output

hanadaa · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: B
Angiotensin converting enzyme (ACE) inhibitors are the mainstays of oral vasodilator therapy for treating chronic heart failure. ACTH is adrenocorticotropic hormone, secreted by the anterior pituitary to stimulate the adrenal cortex. ARBs are angiotensin reuptake blockers, used for the treatment of hypertension. ANB agents are adrenergic neuron blocking agents, such as guanethidine, given for the treatment of hypertension.

Answer to Question 2

ANS: D
The therapeutic outcome of ACE inhibitors in heart failure is to improve cardiac output. ACE inhibitors reduce afterload, inhibit the secretion of aldosterone, and reduce preload.