This topic contains a solution. Click here to go to the answer

Author Question: The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 ... (Read 69 times)

bobypop

  • Hero Member
  • *****
  • Posts: 539
The nurse is assessing an older patient with Parkinson's disease who was started on entacapone 1 week ago. The patient has a history of coronary artery disease and takes an antihypertensive and aspirin.
 
  Which information would support the need for a reduction in medication dosage by the health care provider?
  a. Constipation
  b. Brownish orange urine
  c. Drowsiness
  d. Dizziness

Question 2

What is the pharmacologic action of entacapone, a potent catechol O methyl transferase (COMT) inhibitor?
 
  a. Slows the deterioration of dopaminergic nerve cells
  b. Inhibits the relative excess of dopaminergic activity
  c. Reduces the destruction of dopamine in peripheral tissues
  d. Enhances the cholinergic symptoms of Parkinson's disease



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

katara

  • Sr. Member
  • ****
  • Posts: 305
Answer to Question 1

ANS: D
Dizziness is a symptom of orthostatic hypotension; dosages may need to be altered. Constipation is an expected adverse effect of this medication. Brownish orange urine is an expected adverse effect of this medication. Drowsiness is an expected adverse effect that occurs when therapy is initiated.

Answer to Question 2

ANS: C
Entacapone, a COMT inhibitor, reduces dopamine destruction in peripheral tissues. This significantly increases the amount of dopamine available to reach the brain. Entacapone, when used with carbidopa levodopa therapy, results in more constant dopaminergic stimulation. Entacapone is not effective when used alone. Entacapone does not affect the nerve cells but blocks enzymes that break down levodopa. Parkinson's disease is characterized by a relative deficit of dopaminergic activity. Entacapone does not affect cholinergic symptoms of Parkinson's disease.




bobypop

  • Member
  • Posts: 539
Reply 2 on: Jul 24, 2018
Thanks for the timely response, appreciate it


Animal_Goddess

  • Member
  • Posts: 339
Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

 

Did you know?

No drugs are available to relieve parathyroid disease. Parathyroid disease is caused by a parathyroid tumor, and it needs to be removed by surgery.

Did you know?

Fewer than 10% of babies are born on their exact due dates, 50% are born within 1 week of the due date, and 90% are born within 2 weeks of the date.

Did you know?

In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.

Did you know?

Adolescents often feel clumsy during puberty because during this time of development, their hands and feet grow faster than their arms and legs do. The body is therefore out of proportion. One out of five adolescents actually experiences growing pains during this period.

Did you know?

Today, nearly 8 out of 10 pregnant women living with HIV (about 1.1 million), receive antiretrovirals.

For a complete list of videos, visit our video library