Author Question: Which of the following drug classes is associated with significant differences in metabolism based ... (Read 32 times)

nelaaney · **on:** Jul 24, 2018

Which of the following drug classes is associated with significant differences in metabolism based on gender?

1. Beta blockers
2. Antibiotics
3. Serotonin reuptake inhibitors
4. Angiotensin-converting-enzyme (ACE) inhibitors

Question 2

Gender differences between men and women in pharmacokinetics include:

1. More rapid gastric emptying so that drugs absorbed in the stomach have less exposure to absorption sites
2. Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of distribution
3. Increased levels of bile acids so that drugs metabolized in the intestine have higher concentrations
4. Slower organ blood flow rates so drugs tend to take longer to be excreted