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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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In 2012, nearly 24 milliion Americans, aged 12 and older, had abused an illicit drug, according to the National Institute on Drug Abuse (NIDA).
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Everyone has one nostril that is larger than the other.
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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.