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Author Question: Why do we characterize a meta-analysis as being an observational study (versus an ... (Read 18 times)

olgavictoria

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on: Jul 24, 2018
Why do we characterize a meta-analysis as being an observational study (versus an experiment)?

Question 2

Name three possible problems with meta-analysis.


ecox1012

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Reply #1 on: Jul 24, 2018
Answer to Question 1

THE VARIOUS TREATMENTS CANNOT BE RANDOMLY ASSIGNED ACROSS STUDIES; CONFOUNDING VARIABLES MOST LIKELY EXIST.

Answer to Question 2

ANY THREE OF THE FOLLOWING ARE OK: 1) SIMPSON'S PARADOX; 2) CONFOUNDING VARIABLES; 3) SUBTLE DIFFERENCES IN TREATMENTS OF THE SAME NAME; 4) THE FILE DRAWER PROBLEM; 5) BIASED OR FLAWED ORIGINAL STUDIES; 6) STATISTICAL SIGNIFICANCE VERSUS PRACTICAL IMPORTANCE; 7) FALSE FINDINGS OF NO DIFFERENCE.'


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