How might an amino acid change at a site distant from the active ...

[Hawke]

How might an amino acid change at a site distant from the active site of the enzyme alter the enzyme's substrate specificity?
A) by changing the enzyme's stability
B) by changing the enzyme's location in the cell
C) by changing the shape of the protein
D) by changing the enzyme's pH optimum
E) an amino acid change away from the active site cannot alter the enzyme's substrate specificity

[Sandstorm]

Try C. I remember this question on my exam.

[Hawke]

Thanks, it was correct.