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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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Your heart beats over 36 million times a year.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.