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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
There are more sensory neurons in the tongue than in any other part of the body.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.