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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
Medication errors are more common among seriously ill patients than with those with minor conditions.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.