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By definition, when a medication is administered intravenously, its bioavailability is 100%.
In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
More than 4.4billion prescriptions were dispensed within the United States in 2016.
Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.