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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.