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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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The average human gut is home to perhaps 500 to 1,000 different species of bacteria.
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Medications that are definitely not safe to take when breastfeeding include radioactive drugs, antimetabolites, some cancer (chemotherapy) agents, bromocriptine, ergotamine, methotrexate, and cyclosporine.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.