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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Approximately 70% of expectant mothers report experiencing some symptoms of morning sickness during the first trimester of pregnancy.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%