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The FDA recognizes 118 routes of administration.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Street names for barbiturates include reds, red devils, yellow jackets, blue heavens, Christmas trees, and rainbows. They are commonly referred to as downers.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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In 1864, the first barbiturate (barbituric acid) was synthesized.