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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Egg cells are about the size of a grain of sand. They are formed inside of a female's ovaries before she is even born.
Asthma cases in Americans are about 75% higher today than they were in 1980.

