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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
The use of salicylates dates back 2,500 years to Hippocrates's recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
In 1864, the first barbiturate (barbituric acid) was synthesized.
All adults should have their cholesterol levels checked once every 5 years. During 2009–2010, 69.4% of Americans age 20 and older reported having their cholesterol checked within the last five years.
![Simple food web of an Arctic island. NOTE: The indication of detritivores and pathogens was not part](https://biology-forums.com/gallery/47/medium_33_17_02_12_5_42_58_20001060.jpeg)
![First-pass effect: (a) drugs are absorbed; (b) drugs enter hepatic portal circulation and go directl](https://biology-forums.com/gallery/47/medium_46687_12_12_14_7_07_21_195641052.jpeg)