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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.