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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
Before a vaccine is licensed in the USA, the Food and Drug Administration (FDA) reviews it for safety and effectiveness. The CDC then reviews all studies again, as well as the American Academy of Pediatrics and the American Academy of Family Physicians. Every lot of vaccine is tested before administration to the public, and the FDA regularly inspects vaccine manufacturers' facilities.
Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.
Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.