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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.
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Excessive alcohol use costs the country approximately $235 billion every year.