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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.