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Author Question: Describe the synthesis of acetylcholine. List three different treatments that would act to alter the ... (Read 78 times)

kodithompson

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on: Jun 22, 2018
Describe the synthesis of acetylcholine. List three different treatments that would act to alter the release of acetylcholine.
 
  What will be an ideal response?

Question 2

Explain why blockade of serotonin reuptake is a common drug strategy for the treatment of certain mental disorders.
 
  What will be an ideal response?


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lin77x

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Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: ACh is formed from choline and acetyl-CoA in the presence of choline acetyltransferase. ACh is released into synapses and has effects at 2 receptor types: nicotinic and muscarinic. Action potentials release ACh; botulinum toxin prevents ACh release; black widow spider venom stimulates ACh release.

Answer to Question 2

Answer: Several mental disorders are related to reduced brain levels of serotonin (e.g., depression). Blockade of serotonin reuptake increases synaptic transmitter levels, which would be expected to ameliorate such disorders.


kodithompson

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Reply 2 on: Jun 22, 2018
Thanks for the timely response, appreciate it

ricroger

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Reply 3 on: Yesterday
Gracias!

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