This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Describe the role of the locus coeruleus in the development of opiate withdrawal symptoms. What ... (Read 43 times)

nevelica

  • Hero Member
  • *****
  • Posts: 563
on: Jun 22, 2018
Describe the role of the locus coeruleus in the development of opiate withdrawal symptoms.
 
  What will be an ideal response?

Question 2

Describe the types of approaches that are being taken today to treat drug abuse.
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

brittanywood

  • Sr. Member
  • ****
  • Posts: 355
Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: Withdrawal from opiates results in hyperthermia, pain, nausea, and malaise. Opiate withdrawal can be induced by stopping opiate treatment with the symptoms coming on gradually. Animal studies often use injection of naloxone (an opiate receptor antagonist) to rapidly induce withdrawal. Injection of naloxone into the locus coeruleus (LC) rapidly triggers withdrawal symptoms. Opiates suppress the firing rate of LC neurons but naloxone greatly increases their firing rate. Damage to the LC reduces symptoms of opiate withdrawal.

Answer to Question 2

Answer: One approach is to administer a drug that blocks dopamine receptors, so as to prevent the reinforcing action of the drug of abuse. This, however, can lead to drug craving. Administering a long-acting drug that substitutes for the drug of abuse (e.g., methadone) may help during the drug withdrawal process. A recently developed technique is to develop an antibody to the drug of abuse.


nevelica

  • Member
  • Posts: 563
Reply 2 on: Jun 22, 2018
YES! Correct, THANKS for helping me on my review

lcapri7

  • Member
  • Posts: 350
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.

Did you know?

The most dangerous mercury compound, dimethyl mercury, is so toxic that even a few microliters spilled on the skin can cause death. Mercury has been shown to accumulate in higher amounts in the following types of fish than other types: swordfish, shark, mackerel, tilefish, crab, and tuna.

Did you know?

The most common childhood diseases include croup, chickenpox, ear infections, flu, pneumonia, ringworm, respiratory syncytial virus, scabies, head lice, and asthma.

Did you know?

Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.

Did you know?

More than 50% of American adults have oral herpes, which is commonly known as "cold sores" or "fever blisters." The herpes virus can be active on the skin surface without showing any signs or causing any symptoms.

Hypothyroidism. Hyposecretion of the thyroid gland produces the symptoms that are illustrated. Hypothyroidism. Hyposecretion of the thyroid gland produces the symptoms that are illustrated.
Embryonic Period - Heart Development Embryonic Period - Heart Development
Development of the Reproductive Systems Development of the Reproductive Systems
A Sociological Timeline of Major Figures in the Development of Sociological Theory, 1820–1960 A Sociological Timeline of Major Figures in the Development of Sociological Theory, 1820–1960
Development of a Frog Development of a Frog
Proportional Changes During Skull Development: Human vs. Chimpanzee Proportional Changes During Skull Development: Human vs. Chimpanzee
Video: Red alga life cycle Animation

For a complete list of videos, visit our video library