This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Explain how the reinstatement procedure is used to model drug craving. What will be an ideal ... (Read 14 times)

cdr_15

  • Hero Member
  • *****
  • Posts: 546
on: Jun 22, 2018
Explain how the reinstatement procedure is used to model drug craving.
 
  What will be an ideal response?

Question 2

The ability of THC in marijuana to produce a high seems to be related to activation of the ________ receptor.
 
  Fill in the blank with the appropriate word.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

SVictor

  • Sr. Member
  • ****
  • Posts: 365
Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: Extended experience with a drug results in conditioning of environmental drug cues with the drug state. These environmental cues can elicit craving for the drug during drug abstinence. In the procedure, rats are trained to self-administer a drug for an extended period of time with each lever press accompanied by a variety of cues (pump sound, lights, and perhaps tones). The drug response is extinguished by replacing the contents of the drug syringe with salineover time the pressing ceases. On a test day, the rat receives a free-shot of the drug or experiences the drug cues. The key question is whether the drug prime or the drug cue will reinstate responding on the former drug lever.

Answer to Question 2

Answer: cannabinoid-1 (CB1)


cdr_15

  • Member
  • Posts: 546
Reply 2 on: Jun 22, 2018
Great answer, keep it coming :)

JCABRERA33

  • Member
  • Posts: 344
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

HIV testing reach is still limited. An estimated 40% of people with HIV (more than 14 million) remain undiagnosed and do not know their infection status.

Did you know?

The U.S. Pharmacopeia Medication Errors Reporting Program states that approximately 50% of all medication errors involve insulin.

Did you know?

Signs and symptoms that may signify an eye tumor include general blurred vision, bulging eye(s), double vision, a sensation of a foreign body in the eye(s), iris defects, limited ability to move the eyelid(s), limited ability to move the eye(s), pain or discomfort in or around the eyes or eyelids, red or pink eyes, white or cloud spots on the eye(s), colored spots on the eyelid(s), swelling around the eyes, swollen eyelid(s), and general vision loss.

Did you know?

It is believed that humans initially contracted crabs from gorillas about 3 million years ago from either sleeping in gorilla nests or eating the apes.

Did you know?

Amphetamine poisoning can cause intravascular coagulation, circulatory collapse, rhabdomyolysis, ischemic colitis, acute psychosis, hyperthermia, respiratory distress syndrome, and pericarditis.

Wilson and Simberloff's experiments on the equilibrium model of biogeography. Wilson and Simberloff's experiments on the equilibrium model of biogeography.
Eye Model Eye Model
Axon terminal model Axon terminal model
drug effects at synapses drug effects at synapses
Routes of Drug Administration: Advantages and Disadvantages Routes of Drug Administration: Advantages and Disadvantages
Drug Action Through Channels, via Voltage Changes or Chemicals Drug Action Through Channels, via Voltage Changes or Chemicals
Video: hGH (protein synthesis, growth and development)

For a complete list of videos, visit our video library