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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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It is widely believed that giving a daily oral dose of aspirin to heart attack patients improves their chances of survival because the aspirin blocks the formation of new blood clots.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.