Author Question: Describe the function of agonists and antagonists, giving an example of each and how they affect the ... (Read 51 times)

scienceeasy · **on:** Jun 22, 2018

Describe the function of agonists and antagonists, giving an example of each and how they affect the system to produce their effects.

What will be an ideal response?

Question 2

Draw a diagram that represents a terminal button and postsynaptic neuron. Indicate in this diagram at least five ways that drugs can affect synaptic transmission and give an example of each.

What will be an ideal response?

Amiracle · **Reply #1 on:** Jun 22, 2018

Answer to Question 1

Answer: Answers will vary depending on chosen drugs. Agonists should clearly demonstrate an increase in neurotransmitter action, whereas antagonists should clearly indicate a decrease in neurotransmitter action.

Answer to Question 2

Answer: This would involve the student reproducing Figure 4.7a on page 98.
Possible answers include:
Blockade of synthesis (administration of a drug that inhibits an enzyme required for synthesis.
Administration of a drug such as reserpine that inhibits storage within the vesicles.
Administration of a drug that blocks release of the transmitter (or induces release).
Administration of a drug that binds to and activates the postsynaptic receptors.
Administration of a drug that blocks reuptake of the transmitter.