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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.

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The highest suicide rate in the United States is among people ages 65 years and older. Almost 15% of people in this age group commit suicide every year.

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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.

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Cucumber slices relieve headaches by tightening blood vessels, reducing blood flow to the area, and relieving pressure.

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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.

The small-scale distribution of different tree species in a Douglas-fir forest is determined by both The small-scale distribution of different tree species in a Douglas-fir forest is determined by both
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Video: Stroke volume - contractility definition

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