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In 1864, the first barbiturate (barbituric acid) was synthesized.
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If all the neurons in the human body were lined up, they would stretch more than 600 miles.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.