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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.
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The modern decimal position system was the invention of the Hindus (around 800 AD), involving the placing of numerals to indicate their value (units, tens, hundreds, and so on).