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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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Illicit drug use costs the United States approximately $181 billion every year.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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The people with the highest levels of LDL are Mexican American males and non-Hispanic black females.