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Calcitonin is a naturally occurring hormone. In women who are at least 5 years beyond menopause, it slows bone loss and increases spinal bone density.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Approximately one in four people diagnosed with diabetes will develop foot problems. Of these, about one-third will require lower extremity amputation.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.