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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
Asthma cases in Americans are about 75% higher today than they were in 1980.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.