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In 1864, the first barbiturate (barbituric acid) was synthesized.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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No drugs are available to relieve parathyroid disease. Parathyroid disease is caused by a parathyroid tumor, and it needs to be removed by surgery.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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The human body produces and destroys 15 million blood cells every second.

