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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
On average, the stomach produces 2 L of hydrochloric acid per day.
Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.