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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Nitroglycerin is used to alleviate various heart-related conditions, and it is also the chief component of dynamite (but mixed in a solid clay base to stabilize it).