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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Women are two-thirds more likely than men to develop irritable bowel syndrome. This may be attributable to hormonal changes related to their menstrual cycles.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.