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Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.
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After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
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Cyanide works by making the human body unable to use oxygen.