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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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There are more sensory neurons in the tongue than in any other part of the body.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.