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The use of salicylates dates back 2,500 years to Hippocrates’s recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
Calcitonin is a naturally occurring hormone. In women who are at least 5 years beyond menopause, it slows bone loss and increases spinal bone density.
In 1864, the first barbiturate (barbituric acid) was synthesized.
Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.