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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.
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Medication errors are three times higher among children and infants than with adults.
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Your heart beats over 36 million times a year.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.