Clinical reports reveal that antidepressants may be effective in ...

[clippers!]

Clinical reports reveal that antidepressants may be effective in the treatment of derealization and dissociative identity disorder. However,
 
  A) to be effective, the medications must be administered at the onset of the disorder.
   B) suicidal risk increases with the length of treatment and the degree to which the patient experiences improvement in symptoms.
   C) it is unclear whether the medication works on core symptoms or associated anxiety and depression.
   D) clinical trials reveal that the percentage of patients helped through medication is less than 15.

Question 2

The degree to which a researcher can generalize findings from a randomized controlled design depends on several factors, including type of design, participant selection procedures, internal and external validity, and assessment strategies.
 
  How does each of these elements affect the generalizability of research outcomes?
 
   What will be an ideal response?

[zhanghao]

Answer to Question 1

C

Answer to Question 2

Randomization allows each subject to have an equal chance of being selected. Selection of an analogue or clinical sample limits our conclusions/generalizations based on the nature of the sample. The diversity of the sample would also limit this. Internal validity is affected by the degree to which confounding influences are controlled. As internal validity increases, external validity may decrease because the sample may not reflect conditions in the real world. Finally, the expectations of both the researcher and the subjects (blindedness) may confound the results and our interpretation of them.