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Illicit drug use costs the United States approximately $181 billion every year.
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Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.