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Approximately 70% of expectant mothers report experiencing some symptoms of morning sickness during the first trimester of pregnancy.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
As many as 28% of hospitalized patients requiring mechanical ventilators to help them breathe (for more than 48 hours) will develop ventilator-associated pneumonia. Current therapy involves intravenous antibiotics, but new antibiotics that can be inhaled (and more directly treat the infection) are being developed.
Bacteria have flourished on the earth for over three billion years. They were the first life forms on the planet.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).