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Author Question: A peptide with 12 amino acid residues produced the given fragments when treated with trypsin and ... (Read 71 times)

llesku

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on: Feb 17, 2022
A peptide with 12 amino acid residues produced the given fragments when treated with trypsin and chymotrypsin. Edman degradation of this peptide produced the phenylthiohydantoin derivative of glycine. What is the structure of this peptide?

Trypsin: Gly-Leu-Phe-Arg, Cys-Tyr-Ile-Gly, Val-Trp-Ser-Lys
Chymotrypsin: Gly-Leu-Phe, Ser-Lys-Cys-Tyr, Ile-Gly, Arg-Val-Trp

◦ Val-Trp-Ser-Lys-Gly-Leu-Phe-Arg-Cys-Tyr-Ile-Gly
◦ Gly-Leu-Phe-Val-Trp-Ser-Lys-Cys-Tyr-Ile-Gly
◦ Gly-Leu-Phe-Arg-Cys-Tyr-Ile-Gly-Val-Trp-Ser-Lys
◦ Ser-Lys-Cys-Tyr-Gly-Leu-Phe-Arg-Val-Trp-Ile-Gly
◦ Gly-Leu-Phe-Arg-Val-Trp-Ser-Lys-Cys-Tyr-Ile-Gly
Organic Chemistry ¦ Klein ¦ 4th Edition
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Marked as best answer by llesku on Feb 17, 2022

Rcfelber

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Reply #1 on: Feb 17, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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llesku

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Reply 2 on: Feb 17, 2022
Thanks for the timely response, appreciate it

yeungji

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Reply 3 on: Yesterday
Wow, this really help

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