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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
Studies show that systolic blood pressure can be significantly lowered by taking statins. In fact, the higher the patient's baseline blood pressure, the greater the effect of statins on his or her blood pressure.