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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Historic treatments for rheumatoid arthritis have included gold salts, acupuncture, a diet consisting of apples or rhubarb, nutmeg, nettles, bee venom, bracelets made of copper, prayer, rest, tooth extractions, fasting, honey, vitamins, insulin, snow collected on Christmas, magnets, and electric convulsion therapy.
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People about to have surgery must tell their health care providers about all supplements they take.
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The FDA recognizes 118 routes of administration.