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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Symptoms of kidney problems include a loss of appetite, back pain (which may be sudden and intense), chills, abdominal pain, fluid retention, nausea, the urge to urinate, vomiting, and fever.