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The newest statin drug, rosuvastatin, has been called a superstatin because it appears to reduce LDL cholesterol to a greater degree than the other approved statin drugs.
More than 4.4billion prescriptions were dispensed within the United States in 2016.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
The FDA recognizes 118 routes of administration.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.