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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Illicit drug use costs the United States approximately $181 billion every year.
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Approximately 500,000 babies are born each year in the United States to teenage mothers.
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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.