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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Asthma cases in Americans are about 75% higher today than they were in 1980.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.